| CD15u | Sulphated CD15, 3' sulfated Lewis X |
| Molecule Type | Antigen Expression | Molecular Weight Min / Max |
| Non-lineage Restricted Molecule Carbohydrate | Lymph Node Granulocyte Monocyte Lymphocyte Neutrophil NK Cell Endothelial Cell Bone Marrow Endothelium T Lymphocyte Leukemia cell Myelomonocytic cell |
Expression | ||||||||||
| CD15u is expressed widely on neutrophils, basophils, mature granulocytes, monocytes, NK cells and T lymphocytes but expression on lymphocytes is variable depending on the antibodies used for detection. Expression is present on immature bone marrow cells and on endothelial cells of high endothelium (HEV) of peripheral lymph nodes. CD15u is expressed on myelomonocytic leukemia cells and on adenocarinomas. | ||||||||||
Structure | ||||||||||
| MOLECULAR FAMILY NAME: Belongs to the carbohydrate family. MOLECULAR MASS: No information. POST-TRANSCRIPTIONAL MODIFICATION: No information. POST-TRANSLATIONAL MODIFICATION: No information. | ||||||||||
Ligands | ||||||||||
LIGANDS AND MOLECULES ASSOCIATED WITH CD15u: No information. | ||||||||||
Function | ||||||||||
| CD15u form is the strongest binding partner for CD62P (P-selectin). CD15u is involved with different carbohydrate to carbohydrate cell adhesion. BIOCHEMICAL ACTIVITY: No information. DISEASE RELEVANCE AND FUNCTION OF CD15u IN INTACT ANIMAL: No information. | ||||||||||
Comments | ||||||||||
| MOLECULAR INTERACTIONS - PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF CD15u: No information. SUBSTRATES: No information. ENZYMES WHICH MODIFY CD15u: No information. | ||||||||||
Database accession numbers | ||||||||||
Revised June 25, 2008
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